Thursday, February 21, 2013

Stem Cell Transplant Procedure is Completed

Today Marty completed his stem cell transplant procedure. We are thankful to the LORD that this procedure could be completed, and quite successfully too!

Last Wednesday Marty began a very strong chemo treatment lasting for six days. Two chemo drugs were used -- one on Wednesday - Friday and the second on Saturday - Monday. These chemo treatments went well and on Tuesday, Marty had a "day of rest" from his treatment.   Between yesterday and today Marty had his stem cells, which had been harvested from him several weeks ago, re-injected (transplanted) into his body. The doctors were quite happy with how this transplant went as this can be quite the ordeal for certain patients. Marty himself dealt with all the commotion, discomfort and anything else he was enduring quite well. 

While the harvested stem cells were out of Marty's body, they were frozen. Yesterday five, 60 cc syringes, totalling 300 cc's of stem cells were transplanted back into Marty over about 35 minutes. Present at Marty's bedside in his regular room were: Marty, Erica, Dad Toet, three medical staff who's job it was to thaw the stem cells and load the syringes, one person confirming that the stem cells were actually Marty's, one person who was in charge of the whole procedure, a doctor whose specialty is stem cell transplants, and two nurses to constantly monitor Marty's blood pressure, pulse, and oxygen levels for the duration of the transplant. Marty was on oxygen during the procedure. To say the least, the room was full! Today, it was the same procedure: part two.

Marty received two units of blood which is quite normal for chemotherapy patients to receive. He was very quiet today and over recent days has been confused at times. This could be the result of the chemo treatments. 

Over the past few weeks, Marty's mobility and balance had been slowly regressing. Since starting chemotherapy last Wednesday his mobility and balance has improved somewhat. Naturally this has given Marty more confidence in his ability to get around. Last night he decided to try to make his way to the washroom (a room right in his room) and fell to the floor. At the time there was no one in the room. He was soon discovered and returned to his bed. Thankfully he only suffered a small scratch from his glasses and a small bump on the side of his head!

So now we wait. Ideally the chemotherapy will have dealt a significant blow to Marty's brain cancer -- time will tell. A doctor vaguely noted that perhaps an MRI will be done in a few weeks to see where the cancer's at. We know that these chemo drugs attack not only cancer cells but also red and white blood cells and platelets. So Marty's immune system was attacked by the chemo drugs and rendered virtually non-existent. Hence the stem cell transplant. God, in his wisdom, created stem cells which can become red and white blood cells and platelets as needed. The hope is that the transplanted stem cells, which were spared the chemo treatment, will go back to Marty's bone marrow and then start doing their job: becoming the cells necessary for a "new" immune system. Quite amazing!

"My frame is not hidden from you when I was made in the secret place. When I was woven together in the depths of the earth, your eyes saw my unformed body. All the days ordained for me were written in your book before one of them came to be."
-- Psalm 139:15,16 --

Wednesday, February 13, 2013

Wednesday, Feb 13

Last week we received the disappointing news that Marty's cancer has progressed.  The doctor ordered a MRI of the brain and a CT scan of the body to determine the cause of fevers that Marty had been experiencing. The MRI showed progression of the disease since the last MRI, which was done early January.  The CT scan however came back clean. The doctor immediately put Marty on high dose steroids to minimize his symptoms.  Marty and Erica have decided to continue on with the chemotherapy and the stem cell transplant which was the planned course of treatment.  While this is disappointing news we are comforted by the fact that our heavenly Father continues to uphold and sustain us through all things.  

Today Marty started chemo again.  Due to the fact that this is a very potent form of chemotherapy and that it is secreted through the pores of the skin, Marty will need to have a shower twice a day.  His room will also be given a thorough cleaning twice a day.  The chemo is given through IV and takes approximately 3 hours to complete.  He had his first dose at noon today.  They hope to get the chemo drug from the pharmacy a little earlier tomorrow so that they might be starting it by ten tomorrow morning.   Today, tomorrow and Friday he'll be given Thiotepa (a chemotherapy drug) and for the following three days he'll be given Busulfan (another chemotherapy drug). The risk of this chemotherapy treatment is that it is very potent and will kill good and bad brain cells and also wipe out Marty's immune system causing him to be susceptible to any infection. Without the stem cell transplant he would not be able to grow any new white blood cells, red blood cells or platelets himself.  Some other side effects possibly are mouth sores, nausea, vomitting and diarrhea.  

Following the six days of chemotherapy he'll have his stem cells transplanted back into his body.  Because of the preservative in the  harvested stem cells the transplant will take place over two days; next week Tuesday and Wednesday.  


Marty had a hearty appetite again today which is good to witness. We continue to hold fast to the promises given us by our heavenly Father that not a hair can fall from our head without his will and he will work all things for our benefit.  

 "Cast all your anxiety on him because he cares for you" 
1 Peter 5:7

" But the eyes of the Lord are on those who fear him, 
on those whose hope is in his unfailing love,....
May your unfailing love rest upon us, O Lord, 
even as we put our hope in you. "  
Psalm 33: 18, 22

Saturday, February 2, 2013

Harvest Day 2

Just a brief note to let everyone know that Marty's second day of stem cell harvest went even better than the first.  The count was 2.25 million stem cells per kilogram for a total of 3.83 million stem cells per kilogram.  The doctor is very happy with these numbers.  

Marty did end up going home for the weekend.  We are not sure what the coming week will bring but our heavenly Father knows all and carries us all in the palm of his hand.